Transfection Not Vaccination

Looks like we’ve confused some terminology in the last year when understanding the mechanisms of mRNA in translation as opposed to traditional vaccination strategies. Let me break it down.

Traditionally, scientist combine part of a pathogen with some other agents to elicit an immune response. This fragment of the causative organism should be recognized as foreign by the immune system. The immune system then flags it, memorizes its structure, and destroys it. At the next exposure, the immune system attacks the pathogen before the onset of illness. Illness averted. Novel theory, should everything go as planned.

Moving on, now, to transfection which is actually quite different. It basically makes your body produce the part of the pathogen by inserting a genetic code and using your body to do the creating… and destruction. I’m sure you can see what part of that can be problematic when it comes to the immune system flagging something your body is manufacturing as foreign…?

If you want a visual of this process, Khan Academy is always such a great reference.

mRNA is like a recipe
ribosomes are the kitchen/oven
tRNA is the baker adding ingredients
protein is the cake
Aaand, cake is life… amiright?
Well, proteins are the BUILDING BLOCKS OF LIFE… so they’re kind of a big deal.

This whole process is known as transfection when done with a foreign particles.

So, this time, scientists picked a part of the pathogen, the Spike glycoprotein, for your body to create. Then *hopefully* your immune system destroys (while sparing your self cells) and attacks it at next exposure before onset of illness. Illness averted…? Except this technology has never been used in humans and has gone horribly wrong in animal trials during challenge phases:

*A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge (https://doi.org/10.1128/JVI.06048-11)
*Cellular Immune Responses to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection in Senescent BALB/c Mice: CD4+ T Cells Are Important in Control of SARS-CoV Infection (https://doi.org/10.1128/JVI.01281-09)
*Evasion by Stealth: Inefficient Immune Activation Underlies Poor T Cell Response and Severe Disease in SARS-CoV-Infected Mice (https://doi.org/10.1371/journal.ppat.1000636)
*Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus (https://doi.org/10.1080/21645515.2016.1177688)
*Immunization with Modified Vaccinia Virus Ankara-Based Recombinant Vaccine against Severe Acute Respiratory Syndrome Is Associated with Enhanced Hepatitis in Ferrets (https://doi.org/10.1128/JVI.78.22.12672-12676.2004)
*Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus (https://doi.org/10.1371/journal.pone.0035421)
*Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity (https://doi.org/10.1016/j.jtauto.2020.100051)
*Structural Basis of SARS-CoV-2 and SARS-CoV Antibody Interactions (https://doi.org/10.1016/j.it.2020.09.004)
*Two Different Antibody-Dependent Enhancement (ADE) Risks for SARS-CoV-2 Antibodies (https://doi.org/10.3389/fimmu.2021.640093)
*Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants (https://doi.org/10.1371/journal.pmed.0040080)

Everyone touts how the vaccine stays in your injected muscle and “does not move” about the cabin… what if its ingredients had some questionable qualities that allow it to do just that? You be the judge…

https://www.fda.gov/media/144413/download
https://guardianconsulting.com/wp-content/uploads/2020/12/Moderna-COVID-19-vaccine_FULL_EUA.pdf
https://www.janssenlabels.com/emergency-use-authorization/Janssen+COVID-19+Vaccine-HCP-fact-sheet.pdf

So what are these lipid nanoparticles?
In short, most of the literature is focused on how a lipid nanoparticle can assist a product to pass the blood brain barrier. That’s a little odd. Cell membranes contain lipids so these lipid nanoparticles allow attachment of these mRNA products so that it may enter the cytosol for action. What purpose does the mRNA have specific to the brain? Your guess is as good as mine, but make your own conclusions for the research surrounding lipid nanoparticles (that are in both the Moderna and Pfizer concoctions).

Basophil reactivity to BNT162b2 is mediated by PEGylated lipid nanoparticles in patietnts with PEG allergy (https://doi.org/10.1016/j.jaci.2021.04.032)
Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA (http://doi.org/10.1016/j.nano.2016.12.014)
Development and screening of brain-targeted lipid-based nanoparticles with enhanced cell penetration and gene delivery properties (https://doi.org/10.2147/IJN.S215941)
Enhanced target cell specificity and uptake of lipid nanoparticles using RNA aptamers and peptides (https://doi.org/10.3762/bjoc.17.75)
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein (https://doi.org/10.1016/j.omtn.2021.03.008)
Future considerations for the mRNA-lipid nanoparticle vaccine platform (https://doi.org/10.1016/j.coviro.2021.03.008)
Immune response scenario and vaccine development for SARS-CoV-2 infection (https://doi.org/10.1016/j.intimp.2021.107439)
Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles (https://doi.org/10.3390/pharmaceutics13070945)
Lipid Nanoparticles as Carriers for Bioactive Delivery (https://doi.org/10.3389/fchem.2021.580118)
Lipid Nanoparticles: A Novel Approach for Brain Targeting (https://doi.org/10.2174/2211738506666180611100416)
Lipid Nanoparticle-Mediated Delivery of mRNA Therapeutics and Vaccines (https://doi.org/10.1016/j.molmed.2021.03.003)
Potential SARS-CoV-2 vaccines: Concept, progress, and challenges (https://doi.org/10.1016/j.intimp.2021.107622)
Recent advances in drug delivery applications of cubosomes, hexosomes, and solid lipid nanoparticles (https://doi.org/10.1016/j.apsb.2021.02.013)
SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome (https://doi.org/10.1101/2020.12.12.422516)

Janssen is not spared as it contains polysorbate-80 which does not have the most reassuring SDS. Again, you can decide for yourself…

A Novel Formulation Based on 2,3-Di(tetradecyloxy)propan-1-amine Cationic Lipid Combined with Polysorbate 80 for Efficient Gene Delivery to the Retina (https://doi.org/10.1007/s11095-013-1271-5)
Biologic excipients: Importance of clinical awareness of inactive ingredients (https://doi.org/10.1371/journal.pone.0235076)
Cationic and anionic unloaded polymeric nanocapsules: Toxicological evaluation in rats shows low toxicity (https://doi.org/10.1016/j.biopha.2019.109014)
Complement activation associated with polysorbate 80 in beagle dogs (https://doi.org/10.1016/j.intimp.2012.10.021)
Considerations for the Use of Polysorbates in Biopharmaceuticals (https://doi.org/10.1007/s11095-018-2430-5)
COVID-19 Vaccine-associated Anaphylaxis and Allergic Reactions: Consensus Statements of the KAAACI Urticaria/Angioedema/Anaphylaxis Working Group (https://doi.org/10.4168/aair.2021.13.4.526)
Non‐IgE‐mediated hypersensitivity induced by multivitamins containing Tween‐80 (https://doi.org/10.1111/1440-1681.13089)
Reducing or Eliminating Polysorbate Induced Anaphylaxis and Unwanted Immunogenicity in Biotherapeutics (https://www.neurelis.com/sites/default/files/pdf/Reducing%20or%20Eliminating%20Polysorbate%20Induced%20Anaphylaxis%20and%20Unwanted%20Immunogenicity%20in%20Biotherapeutics.pdf)
Successful SARS-CoV-2 vaccine allergy risk-management: The experience of a large Italian University Hospital (https://doi.org/10.1016/j.waojou.2021.100541)
Surface-modified polycaprolactone nanoparticles for the brain-targeted delivery of nevirapine (https://doi.org/10.1007/s11051-020-04831-9)

At the very least, these investigational products are just that… under investigation. And, no, nobody should be allowed to coerce you with free food, cars, money, lottery, employment retention, or otherwise to be part of this gene therapy exercise and be totally free from liability. We have be here before and it was not pretty. More on that to come.

Shalom, light, and love…

In a World of Mandatory Vaccines

At the end of the day, you either have rights to your own body or you don’t.

Hypothetically, let’s explore a world of mandatory vaccines. How would compliance look…?


You send your baby to daycare. Your baby gets their mandated vaccines during their time at daycare. The majority of vaccines are given from birth to two years of age. Baby comes home with several bandaids after their “update” and you aren’t made aware of what was given… why? Because they’re mandatory and your opinion doesn’t matter. Even if you didn’t want them to have the flu shot with the thimerosal, it is not your choice because that is what was available (multidose vials are cheaper) and it was your baby’s shot day.

You send your kids to public/private school and they come home saying they got a shot today. You were never notified nor informed (because they are mandatory, so it doesn’t matter). What shot? Doesn’t matter — mandatory. Flu, HPV, Heplisav-B (with a new adjuvant and myocardial infarction marker), HIV (clinical trials currently), Ebola (created Dec 2019), etc. If it shows up on the schedule, it is mandatory. Maybe it wasn’t tested in this age group, but now it will be because it is on the official schedule. That is how the ACIP approves use… no studies, just data collection after it has been put to market.

In another scenario, a practitioner goes door-to-door for mandatory shots. They can come into your home, because the state says they’re mandatory (you do not have a choice). Homeschool households are brought “up to date” on current govt mandated medicines, despite a risks v. benefit analysis.

Vaccines brought to your workplace, stores, and neighborhoods. Either you get the shots or you are segregated from attending school, work, or public places. Does this not sound a bit familiar?


This. Is. Not. Okay. This is a slippery slope to becoming the object of Big Pharma’s needs. The same people that brought you the opioid epidemic, tobacco science, thalidomide, Vioxx, etc… create vaccines. How can we see the constant lawsuits in the press, yet fully support the same companies on the very products that have never been tested synergistically in our babies and children? How have we given this industry a free ticket to give our children products that have NEVER been subject to rigorous safety testing using an inert placebo for comparision? The “science” is junk.

How did this happen?

If the outcome was obvious (e.g., healthier children, longer lifespan), then parents would line up to get their children innoculated. Parents are witnessing the opposite. We ask for the science and what happens? We are vilified, bullied, and harassed… there is your red flag, folks!

The science is never settled, it evolves. This “science” is reductionist and outdated. The safety science is lacking (see World Health Organization conference Dec 2019). Fund the unbiased study comparing vaccinated vs. unvaccinated populations. People will volunteer their kids to be part of the unvaccinated cohort (if your problem is “ethics” of not adminstering the biologics).

If compliance has to be mandated and censorship is enforced, perhaps there is a problem with the product.

At the end of the day, who is in charge of your wellbeing? If they were so concerned about health, lawmakers would mandate clean water and good nutrition. Lawmakers would outlaw non-nutritive snack machines in schools. Yet, those things would not increase any big business profit margins, would they? Health doesn’t create lifelong customers for pharmaceutical giants.


Shalom, light, and love.



Sites to consider:
https://thehighwire.com/ignored-warnings-an-unauthorized-history-of-the-who/

Disease is NOT Normal

STOP NORMALIZING asthma, chronic ear infections, eczema, food/seasonal allergies, and neurocognitive delays. What are we doing to our immune systems that is causing these OVER-REACTIONS in our children?

Vaccines contain adjuvants that are designed to create an immune RESPONSE. Perhaps these doses of adjuvants are creating an OVER response? With any pharmaceutical there is a possibility of overt action…

》too much blood pressure medication = low BP
》too much insulin = low sugar
》too much antibiotic = bye-bye biome balance, hello opportunistic virulent and resistant organisms
》too much immune system suppression = no immune response, risk for illness

What about too much immune system stimulation? What happens when your immune system is on high alert and you eat an allergenic food at the same time? What happens when you’re given this stimulation repeatedly as a newborn with an IMMATURE immune system that still prioritizes Th2 (inflammatory) response over a Th1 (antibody) response?

That sounds like chronic inflammation. Alike… asthma, chronic ear infections, eczema, and food/seasonal allergies. The neurologic disorders may be a byproduct of heavy metal exposure (we see this with Alzheimers and aluminum in brain tissues as well as brain disorders with Cobalt hips). There is potential here, too!

Newborn immune systems lack memory and are tolerant of antigens for a reason. Babies are born sterile. They are still learning boundaries and creating the flora in their bowels that will become a major component of their immune system for their lifetime. If their body created a Th1 response to every foreign substance, they wouldn’t survive in this world… as we live in symbiosis with the microbes on our skin, in our airway, and in our bowels. Newborns must be colonized with these organisms and build up those systems. How does chronic stimulation of the immune system fit into this matrix?

It does not make sense. Vaccines are given in several doses to “create antibodies” though we know that more are added because they are ineffective in doing that in the first 2-3 doses… probably due to lack of the Th1 response, eh? So, now we give these tiny bodies several doses of adjuvant along with a fragment of a genetic component or microbe without considering what complexes are made between those simultaneous IM exposures, nor do we even study them.

The ACIP, advisory council for immunization practices, does not perform nor require adequate studies! They STATE that fact in these meetings.

So, if you still think that the voice of several thousand concerned mothers and fathers is horsebalogna, your cognitive dissonance is strong. We don’t do this to create drama. We do this to create safer practices for future generations. Mothers and fathers should not have to prove that these practices are harmful. Robust scientific evidence (not industry jargon) should prove interventions to be SAFE before subjecting our most vulnerable populations to them. Concerns should be addressed with valid studies (again, not industry jargon).

Pharmaceutical studies are done on adult populations and medications are recalled for adverse events… I think it is time for a recall, but “biologics” are not considered ‘medications’ for that exact reason…

Are we trading short-term infection for long-term disease?

Are we damaging immune systems by overstimulating them in their development?

When do we start paying attention to the parents that witness their children’s struggle to breathe, eat, and feel well? A normal child should not battle painful skin, constant stomach disturbances, nor frequent episodes of intense ear infections. This was not our (parents born before 1995) reality of childhood and must be questioned.

Shalom, light, and love.

5 Examples of Slow or Shady Science

If you struggle with new ideas, have you researched cognitive dissonance? Science is pretty funny, let us revisit a few things…

1. Infections in laboring women (puerperal sepsis, “childbed fever”) used to be rampant in hospitals, so much so that women would rather birth in the streets. A doctor researched the differences between birthing in areas of low postpartum infection and high postpartum infection. He discovered handwashing would prevent mothers from dying. This practice, simple handwashing, took OVER TWENTY YEARS to come to light. That doctor (Ignaz Semmelweis) was ridiculed and pushed out of medicine. I am serious. He was also beaten to death in a mental asylum, though the facts surrounding that are suspect.

2. Smoking used to be touted as good for health! Doctors used to promote smoking, a majority smoked themselves. Scientists started to uncover the harms of tobacco and the first study was published in 1939. The tobacco industry struck back by funding fake science to promote their products. It took 26 YEARS for health warnings to be administered by the Surgeon General about the risks of smoking. Funding science from conflicts of interest did not end with tobacco products; other entities now manipulate research and saturate the market with false science.

3a. Dr. Marcia Angell, former Editor-in-Chief of the New England Journal of Medicine, the most respected medical journal, stated that clinical research is steeped in conflicts of interest and people are paid to sway studies for the benefit of large pharmaceutical companies.

3b. Dr. Richard Horton, current Editor-in-Chief of The Lancet, another highly respected medical journal, states that half of the science is UNTRUE. Half! Studies are falsified, controls are used to influence outcomes, and we can no longer take them at face value as there are heavy conflicts of interests straight from drug manufacturers who fund these studies.

3c. Former Director of National Institutes of Health, Dr. Bernadine Healy, constantly dealt with science fraud and even stated that not looking into something because of pressures from industry should throw red flags, yet this is happening. At the very end of this clip, she speaks on a statement from the IOM that discourages research. The Institutes of Medicine have issued warnings of looking into matters because they are afraid of what it will show. These are topics that influence our children!

4. A senior vaccine safety research scientist within the Centers for Disease Control holds whistleblower status. Dr. William Thompson tried to uncover the fraud with the creation and efficacy studies for the MMR vaccine. He has to have permission from the Director of the CDC to testify, he has still not been granted permission. Surprised?

5. ALL infant vaccines state in section 13.1 of the insert that “[vaccine name] has not been evaluated for carcinogenic or mutagenic potential, or for impairment of fertility.” This is not studied. We put these biologics into newborns fresh from the womb and every two-three months up to their first birthday and beyond. These things are not studied, and yet we tout them as “safe and effective.” Infants double their birth weight by six months of age and triple their birth weight by their first birthday. This is a period of rapid growth and development, wouldn’t it be keen to have studies performed on carcinogenic or mutagenic potentials at the VERY least?

Cognitive dissonance is real and Semmelweis reflex happens today. We need to partner with providers within our community to lead and support us to better health practices. It is up to parents to question current practices as they see changes in their children (or their friends/family). Medical professionals are busy, but need to make research a priority. They may need a vaccine insert given to them directly with the plea of a concerned parent. There are physicians that are changing the course of healthcare for our children, they are starting to see problems. Informed consent must be protected and touted as the bare minimum, and we need to keep providers accountable. Healthcare practitioners are charged to give true informed consent, constantly weighing risks versus benefits. Downplaying risks or negating them all together is not true informed consent: it is an agenda.

Shalom, light, and love.

 

Sites to Consider:
https://www.npr.org/sections/health-shots/2015/01/12/375663920/the-doctor-who-championed-hand-washing-and-saved-women-s-lives
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470496/
http://tobaccocontrol.bmj.com/content/21/2/87
NEJM editor: “No longer possible to believe much of clinical research published”
http://www.collective-evolution.com/2015/05/16/editor-in-chief-of-worlds-best-known-medical-journal-half-of-all-the-literature-is-false/
https://www.acsh.org/news/2015/05/19/science-publication-is-hopelessly-compromised-say-journal-editors
List of vaccine inserts: http://www.vaccinesafety.edu/package_inserts.htm

Let’s Talk About Parental Rights and Responsibilities

When you decide to have a child, it’s a big deal. You are in charge of another human life for at least the next 18 years. Sometimes this is longer. When you decide to have a child, you fear all of the unknowns. You are terrified of messing it up, so you research just about everything…

You look for the safest car seat. You spend hours on various safety websites. You compare brands and testimonies. You make sure it fits your car. You even find the safest seat in your car. You may (and should) get it inspected by a certified car seat inspector for proper securement. Some even buy a whole new car when they’re expecting! We did… a few times.

You look for the best crib and mattress. You’re scared to death of SIDS (which, by the way, is not suffocation) so you look for a breathable mattress. Maybe it is hypoallergenic or some fancy cooling gel type. You spend time comparing reviews.

You look for a sleeper for an additional place to sleep. You know infants sleep a lot and want eyes on them all the time, so you buy a sleeper. You might want them in your room for the first few weeks or months and can’t fit the crib, so you buy a sleeper. You don’t buy any sleeper, you buy the one that rocks, changes positions, and plays music or soothing sounds. You buy the one that gets the best ratings. You want ultimate comfort for your baby.

You look for a stroller. Does it come with the car seat? What if I want one for jogging or different terrain? Are the tires plastic or rubber? Does it come with a weather shield? Maybe you opt to buy a baby carrier. Which one is the most comfortable? Should I try babywearing? What brands are the best? You read and read.

You look for a diaper bag. Am I going to carry bottles? How many pockets does it have? Does it have extra cooling space? Can I wash it? Do I like the straps? How many diapers will it fit? How much clothing can I pack?

You look at diapers. You have a friend that uses cloth, maybe you look into it and reach out to her. What about disposables? Which is cheapest? What brand is best? Which ones won’t give my baby a rash? What about rash cream? I need some of that too, right? You look into it.

You research some of these things, maybe all of them, maybe more… because this is YOUR baby. You care for them. The minute they hit your chest, your whole world is different. You have a fierce love for this tiny human. You will do anything for them; then the nurse comes at them with a needle. They cry. You cry. Did you ever look into it? Did you ever look at newborn interventions? You had a birth plan, did you include your baby? If so, you did a lot more research. You looked at cord clamping, skin-to-skin, and indications for “eye goop.” You looked up newborn vaccinations.

The hospital or staff told you it was routine. They told you it was mandatory, and they had to have them, but is this YOUR child or does this new baby belong to the hospital? Does this baby belong to the pediatrician? Do they belong to the government? How about your state? Do you think this baby belongs to the CDC? After all, they are the ones who proposed the vaccination schedule. The CDC and ACIP (Advisory Committee on Immunization Practices) are the ones that recommend the vaccines. Do they own your child? No? Then why are they making decisions for your child?

You should look up the schedule. You should research the diseases, their history, and their treatment. You should research the vaccines. You have the ability at your fingertips. You are the parent. This is your responsibility. You did it for everything else, so why is this someone else’s territory? These substances go into your newborn’s body. This developing infant gets these biologics… you should know what they are. This is your baby. This is your responsibility. If you want to pass that responsibility off to another person, go for it. That is your choice. Nothing about that is “normal.” Passing off parental responsibility should not be seen as the norm. What should be seen as the norm is parents making informed decisions and having open discussions with healthcare professionals. That should be normal.

Remember, most doctors are not scientists. They don’t usually know the intricacies of vaccine manufacturing, “screening,” testing, approval, courts, payouts, and events reporting. Pediatricians follow protocols mandated upon them by entities that don’t go to med school. Even medical journals are becoming drug advertisements (see video). The art of medicine has been drained by corporate interests, demands of insurance companies, and government protocols. Doctors have been shackled to mandates from people who haven’t been to med school. Providers worry more about litigation than medicine. They cannot deviate, for they will be questioned. Even if it is in the best interest of the patient, they are forced to do otherwise. There is no money in wellness. Think about that. It is no secret that we have the sickest developed nation, and our children are now subject to our poor health habits. Something isn’t working, and we all know governments destroy just about everything. They destroy our money, relationships with other countries, relations within our society with the help of mainstream media, personal rights (there is no shortage of that). So, back to those rights…

Right to body autonomy means that you have ownership of your body. It is your own and you control it. This also goes for your children. They own their body and have the right to their body. You make decisions for them, until they have the mental capacity to do so for themselves. If you didn’t have body autonomy, you could be taken from your home for no reason, imprisoned, tested upon. Somebody could break your bones, stab you, beat you and you’d have no recourse. If you don’t own your body, who does? Right to bodily autonomy is the foundation of liberty.

How is it that in today’s America, in what’s supposed to be a “freed” country, parents are pushed around by health care professionals and government bodies to inject biologics into their children? How is that possible? This is not individual liberty. This is a medical mandate reminiscent of Hitler’s Nazi Medical Experiments.

It is time to rise, parents. You are raising future America. Is it going to be a place where adults don’t believe they have a right to their body? Will it be a place where the government decides who gets what medical interventions? What happens when millions are maimed and killed by said interventions? Without the right to body autonomy, you won’t have a choice, and they won’t have a consequence. Sounds like the predicament we already face with our infants.

Children are the responsibility of their parents, let’s not diminish that role. Parents need to arm themselves with knowledge. Read like you did when preparing for a newborn and baby-proofing your home. We must empower ourselves and each other with the strong message of being responsible for our children (and self) and becoming more educated. There is always more to learn.

Shalom, light, and love.

 

Sites to consider:

https://www.kevinmd.com/blog/2018/02/week-worst-health-care-system-world.html
https://mises.org/library/law
http://icandecide.org/about/
https://qz.com/1201360/im-a-law-professor-and-i-teach-my-students-how-to-destroy-american-democracy/
https://www.msn.com/en-us/news/newsphotos/the-healthiest-and-least-healthy-nations-in-the-world/ss-AAaprFO#image=1 (US doesn’t make this list, not surprised)
http://www.newsweek.com/united-states-health-care-rated-worst-637114